Calretinin, a 29kD calcium binding protein found mostly in the central nervous system and retina.
It is a cytoplasmic protein involved in the regulation of calcium concentration, which is important in the regulation of a large variety of neuronal functions, including neurotransmitter release, ionic channel permeability, enzyme activity, and gene transcription.
Mice deficient in calretinin show impairment in motor coordination.
Calretinin has also been shown as a sensitive and specific marker for mast cells.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000Immunohistochemistry (Frozen): 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:sheep
Source Antibody:guinea pig
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in Tris. No preservative added.
Specificity:Recognizes guinea pig Calretinin. Species Crossreactivity: rat
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Gp Rt
Immunogen:Purified guinea pig calretinin. Species Sequence Homology: human, mouse and primate