Recognizes an epitope within the N-terminal (NT) region of Adiponectin Receptor protein 1 (AdipoR1), a highly conserved and ubiquitously expressed integral membrane protein and member of the ADIPOR family, which acts a receptor for the adipocyte-secreted antidiabetic hormone adiponectin (APM1).
AdipoR1 is implicated in metabolic pathways, mediating increased fatty acid oxidation and glucose uptake by adiponectin.
The expression of AdipoR1 in adipose tissue is decreased in obese humans, whilst weight loss results in increased expression
It is reported as suitable for use in immunocytochemistry of acetone fixed cell
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Immunohistochemistry (Paraffin): 1:250Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.1% BSA, 0.09% sodium azide.
Specificity：Recognizes human AdipoR1.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to SSHKGSVVAQGNGAPASNREADTVE aa2-26 within the N-terminal region of human AdipoR1.
