84-2264-36　［取扱停止］Melanoma, gp100 (95kD Melanocyte Specific Secreted Glycoprotein, D12S53E, ME20, ME20M/ME20S, Melanocyte Lineage Specific Antigen GP100, Melanocyte Protein Mel 17, Melanocyte Protein Pmel 17, Melanoma Associated ME20 Antigen, Melanosomal Matrix Protein 17, PMEL17, SI, SIL, SILV) (FITC) 100ul　M2870-02F-FITC

特徴

• Melanoma gp100 a melanosomal matrix protein whose expression is closely correlated with cellular melanin content and which is a frequent melanoma tumor antigen recognized by cytotoxic T lymphocytes.
• It is a likely candidate gene for some cases of human oculocutaneous albinism not associated with known albinism loci.
• The gp100 protein is the most abundant glycoprotein in nucleated mammalian cells.
• The gp100 antigen is highly expressed in melanocyte cells, and recognized by cytotoxic T lynphocytes.
• The gp100 protein is known to initiate cellular immune response through the interaction with mature dendritic cells (DCs).
• GP100/PMel17 is a melanoma differentiation antigen, which is observed as the target of tumor infiltrating lymphocytes (TIL) and has therefore been proposed as an immunotherapeutic agent in malignant melanoma.
• Applications:Suitable for use in Peptide ELISA and Western Blot.
• Other applications have not been tested.
• Recommended Dilutions:Optimal dilutions to be determined by the researcher.
• Storage and StabilityStore product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.