This gene encodes subunit 3 of the splicing factor 3a protein complex.
The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing.
Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP.
This gene has a pseudogene on chromosome 20.
Applications:Suitable for use in Immunoprecipitation, Immunofluorescence, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:200-1:2000Immunoprecipitation: 1:20-1:50Immunohistochemistry: 1:50-1:200Immunofluorescence: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes SF3A3. Species Crossreactivity: human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:IF IHC IP WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Recombinant protein corresponding to human SF3A3.