84-2241-08　［取扱停止］RGR (RPE-Retinal G protein-Coupled Receptor, RP44) 100ul　213095

特徴

• This gene encodes a putative retinal G-protein coupled receptor.
• The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family.
• Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain.
• The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal.
• The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells.
• The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells.
• This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively).
• Alternative splicing results in multiple transcript variants encoding different isoforms.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.