This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator.
This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation.
Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene.
Applications:Suitable for use in Western Blot, Immunoprecipitation.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunoprecipitation: 1:20-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes RBM14. Species Crossreactivity: human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:IP WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to human RBM14.