84-2238-79　［取扱停止］RAD18 (Postreplication Repair Protein hRAD18p, Postreplication Repair Protein RAD18, RAD18 Homolog, RAD18 (S. cerevisiae) Homolog, RING Finger Protein 73, RNF73) 50ul　212981

特徴

• The protein encoded by this gene is highly similar to S.
• cerevisiae DNA damage repair protein Rad18.
• Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA.
• Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif.
• Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
• Applications:Suitable for use in Immunofluorescence and Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.