84-2233-55　［取扱停止］PRKAA1, phosphorylated (T174/T172) (AMP Activated Protein Kinase alpha1, AMPK, AMPKa1, MGC33776, MGC57364) 50ul　212764

特徴

• The protein encoded by this gene belongs to the ser/thr protein kinase family.
• It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK).
• AMPK is a cellular energy sensor conserved in all eukaryotic cells.
• The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio.
• AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation.
• It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
• Alternatively spliced transcript variants encoding distinct isoforms have been observed.
• Applications:Suitable for use in Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.