The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases.
These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation.
This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
The ANGPTL7 gene is located in an intron of this gene.
Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:100Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes human MTOR, phosphorylated S2448.
Isotype:IgG
Calc Applications Abbrev:IF IHC WB
Calc Crossreactivity:Hu
Immunogen:Phospho specific peptide corresponding to residues surrounding S2448 of_+E_human MTOR.