84-2216-91 [取扱停止]MLH1 (Human Mul L Homologue, Familial Nonpolyposis Colin Cancer Type 2, COCA2, Colon Cancer Type 2, COCA2, FCC2, HNPCC, HNPCC2, MGC5172, hMLH1) 200ul 212010
特徴
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC).
It is a human homolog of the E.
coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Additional transcript variants have been described, but their full-length natures have not been determined.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes MLH1. Species Crossreactivity: human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Recombinant protein corresponding to human MLH1.
Shelf Life:1year
Swiss Prot Number:P40692
EU Commodity Code:30021010
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