84-2206-27　［取扱停止］Integrin beta 7 (ITGB7, integrin, beta 7) 200ul　211520

特徴

• This gene encodes a protein that is a member of the integrin superfamily.
• Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell.
• Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.
• The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion.
• Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches.
• Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule.
• Alternate splicing results in multiple transcript variants.
• Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.