84-2202-77　［取扱停止］HSPA9 (Heat Shock 70kD Protein 9, CSA, GRP75, HSPA9B, MGC4500, MOT, MOT2, MTHSP75, PBP74, mot-2) 100ul　211376

特徴

• Grp75, also known as mortalin, is a member of Hsp70 family of chaperone proteins that is not heat-inducible (1,2).
• This protein is essential for transporting many mitochondrial proteins from the cytoplasm to mitochondria (3).
• Grp75 inactivates the tumor suppressor p53 (4).
• Studies found that Grp75 is overexpressed in many tumor tissues and immortalized human cell lines, suggesting its role in the tumor formation (5).
• Grp75 is also implicated in cell aging, as its overexpression appears to prolong the life span of human fibroblasts (6).
• Applications:Suitable for use in Immunofluorescence and Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.