84-2198-28　［取扱停止］HDAC4, phosphorylated (S632) (Histone Deacetylase 4, HD4, AHO3, BDMR, HDACA, HA6116, HDAC-4, HDAC-A) 50ul　211193

特徴

• Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.
• Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
• The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family.
• It possesses histone deacetylase activity and represses transcription when tethered to a promoter.
• This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D.
• It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.