This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily.
Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene.
The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade.
This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing.
Related pseudogenes have been identified on chromosomes 7 and 14.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes ELK1, phosphorylated S383. Species Crossreactivity: human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Phospho specific peptide corresponding to residues surrounding S383 of human ELK1.