84-2186-33 ［取扱停止］EIF6 (Eukaryotic Translation Initiation Factor 6, CAB, EIF3A, eIF-6, p27BBP, ITGB4BP, b(2)gcn, p27(BBP)) 50ul 210663
特徴
- Eukaryotic initiation factor 6 (eIF6) is reqiured for the 60S ribosomal subunit assembly in the nucleolus (1).
- In the cytoplasm, this protein is bound to 60S ribosome subunits and prevents them from joining 40S ribosome subunits to form 80S ribosomes (2).
- eIF6 is also shown to associate with the RNA-induced silencing complex (RISC) (3).
- Deletion of eIF6 abolishes the miRNA-mediated gene silencing (3).
- eIF6 may play its essential role in miRNA-mediated silencing by inhibiting translation initiation or ribosome recycling (3).
- Applications:Suitable for use in Immunofluorescence and Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：50ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by affinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes EIF6. Species Crossreactivity: human, mouse, rat
- Isotype：IgG
- Calc Applications Abbrev：IF WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Recombinant protein corresponding to human EIF6.
- Shelf Life：1year
- Swiss Prot Number：P56537
- EU Commodity Code：30021010
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