84-2183-05　［取扱停止］DNMT3A (DNA-methyltransferase 3A, DNMT3A2, M.HsaIIIA) 100ul　210517

特徴

• CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation.
• Studies in mice have demonstrated that DNA methylation is required for mammalian development.
• This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation.
• The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
• Alternative splicing results in multiple transcript variants encoding different isoforms.
• Applications:Suitable for use in Immunofluorescence and Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.