84-2180-83　［取扱停止］DCTN2 (Dynactin Subunit 2, DCTN50, DYNAMITIN, RBP50) 100ul　210413

特徴

• Dynamitin is a 50kD protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain.
• This protein is a part of the dynactin complex believed to link the dynactin complex to membrane compartments.
• Its functions are tightly associated with dynein motor protein, thus extend to vesicle trafficking and membrane integrity.
• Dynamitin was named so because its overexpression causes dynactin complex which contains 10 subunits, to disassemble.
• Its N terminal 58 amino acid is for MacMARCKS binding and residues 59-83 is responsible for calmodulin binding.
• This antibody is against the full length p50 dynamitin.
• Applications:Suitable for use in Immunofluorescence and Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.