This gene encodes the peroxisomal enzyme D-amino acid oxidase.
The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group.
Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids.
Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging.
In mice, it degrades D-serine, a co-agonist of the NMDA receptor.
This gene may play a role in the pathophysiology of schizophrenia.
Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes DAO. Species Crossreactivity: human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to human DAO.
