84-2172-29　［取扱停止］CDC25A, phosphorylated (S76) (Cell Division Cycle 25A isoform a, CDC25M3, M Phase Inducer Phosphatase 1, MPIP1) 50ul　210025

特徴

• CDC25A is a member of the CDC25 family of phosphatases.
• CDC25A is required for progression from G1 to the S phase of the cell cycle.
• It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups.
• CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division.
• CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.
• Two transcript variants encoding different isoforms have been found for this gene.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.