84-2168-80　［取扱停止］Camk2a, phosphorylated (T286) (Calcium/Calmodulin-dependent Protein Kinase Type II Subunit alpha, CAMKA, KIAA0968) 50ul　209862

特徴

• The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily.
• Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses.
• This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta.
• The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning.
• In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.
• Two transcript variants encoding distinct isoforms have been identified for this gene.
• (provided by RefSeq, Nov 2008)
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.