84-2155-84　Macrophage Inflammatory Protein 1 alpha (MIP-1 alpha, CCL3, LD78 alpha) (HRP) 100ul　M1202-30A-HRP

特徴

• Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines.
• They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g.
• macrophages, lymphocytes and NK cells.
• While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes.
• Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells.
• Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells.
• Applications:Suitable for use in ELISA, Western Blot and Neutralization.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.