84-2153-37 ZIC2 (Zic family member 2 (odd-paired homolog, Drosophila), HPE5, Zic family member 2 (odd-paired Drosophila homolog), Zinc finger protein of the cerebellum 2, Zinc finger protein ZIC 2) 100ug 208513
84-2153-37 ZIC2 (Zic family member 2 (odd-paired homolog, Drosophila), HPE5, Zic family member 2 (odd-paired Drosophila homolog), Zinc finger protein of the cerebellum 2, Zinc finger protein ZIC 2) 100ug 208513
Zinc finger protein ZIC2 is a member of the GLI C2H2-type zinc-finger protein family.
This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1.
Gene mutations cause holoprosencephaly type 5 in human brain and neural tube defects.
Recent studies show that complete deficiency of the related murine ZIC2 transcription factor can also be a contributing factor to variable midline deficiencies, presenting during mid-gastrulation and similar forebrain anomalies.
Applications:Suitable for use in Peptide ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Peptide ELISA: 1:1000Western Blot: 0.5-2ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes human ZIC2. This antibody is expected to NOT cross-react with other ZIC proteins.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to C-HSGLSSNFNEWY, from the C-terminus of the protein sequence according to NP_009060.2. Species sequence homology: mouse, rat, canine and bovine