84-2152-84 THBS1 (Thrombospondin 1, THBS, TSP, TSP1, Thrombospondin-1p180) 100ug 208461
特徴
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions.
Binds heparin.
May play a role in dentinogenesis and/or maintenance of dentin and dental pulp By similarity.
Ligand for CD36 mediating antiangiogenic properties.
Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors By similarity.
Applications:Suitable for use in Peptide ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Peptide ELISA: 1:128,000 (detection limit)Western Blot: 0.1-0.3ug/ml.
In transfected HEK293 transiently expressing human THBS1 a band of ~200kD plus a breakdown product are observed.
These bands are not observed in the non-transfected HEK293.
The calculated molecular size is 129kD according to NP_003237.2
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes human THBS1.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Peptide corresponding to NRIPESGGDNSVFD-C, from the N-terminus of human THBS1 (NP_003237.2). Species sequence homology: mouse, rat
Shelf Life:1year
EU Commodity Code:30021010
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