Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity.
Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4.
Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2.
Applications:Suitable for use in Peptide ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Peptide ELISA: 1:64,000Western Blot: 0.05-0.2ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human NTRK2. This antibody is expected to recognize isoforms a (NP_006171.2), b ((NP_001007098.1), c (NP_001018074.1), d (NP_001018075.1), e ( NP_001018076.1).
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-KTLQEAKSSPDTQ, from the internal region of the protein sequence according to NP_006171.2; NP_001007098.1; NP_001018074.1; NP_001018075.1; NP_001018076.1. Species sequence homology: mouse, rat and canine
