Neurogenin1 (neurog1, ngn-1) is a basic helix-loop-helix gene and a member of the neurogenin category of genes.
These genes are involved in expression of differentiation genes such as NeuroD and function as determination factors.
Neurog1 is necessary to the development of all zebrafish cranial ganglia.
Neurog1 regulatory elements are conserved among vertebrates, and function is partially conserved as well.
The upstream region of zebrafish neurog1 is capable of recapitulating endogenous expression in both the zebrafish and mouse telencephalon.
Neurog1, along with achaete/scute homologue 1a, functions downstream of the homeodomain transcription factor floating head to regulate epiphysial neurogenesis.
Delta/Notch signaling represses neurog1 activity to promote the formation of the zebrafish neural crest.
Applications:Suitable for use in Peptide ELISA.
Other applications not tested.
Recommended Dilutions:Peptide ELISA: 1:32,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：Zebrafish
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography
Form：Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Specificity：Recognizes zebrafish Neurog-1.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Ze
Immunogen：Synthetic peptide corresponding to C-SHTDDEDSRSSLH, from the internal region of zebrafish Neurog-1
