The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis.
The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family.
Mutations in this gene have been linked to exertional myoglobinuria.
Multiple transcript variants encoding different isoforms have been found for this gene.
The human genome contains several non-transcribed pseudogenes of this gene.
[provided by RefSeq, Sep 2008].
Applications:Suitable for use in Peptide ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Peptide ELISA: 1:64,000Western Blot: 0.3-1ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes human LDHA. This antibody is expected to recognize isoform 1, 2 and 3 (NP_005557.1; NP_001128711.1; NP_001158886.1).
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to C-SDLVKVTLTSE, from the C-terminus of the protein sequence according to NP_005557.1; NP_001128711.1; NP_001158886.1.