Required for activity of the Ah (dioxin) receptor.
This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding.
The complex then initiates transcription of genes involved in the activation of PAH procarcinogens.
The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
Applications:Suitable for use in Peptide ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Peptide ELISA: 1:64,000Western Blot: 1-3ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human ARNT. This antibody is expected to recognize all reported isoforms (NP_001659.1; NP_848514.1; NP_001184254.1).
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa558-570 from sequence C-SEIYHNINADQSK, at the internal region of the protein sequence according to NP_001659.1; NP_848514.1; NP_001184254.1. Species sequence homology: canine
