Mimicking phosphorylation at serine 87 inhibits the aggregation of human a-synuclein and protects against its toxicity in a rat model of Parkinson's disease.
Applications:Suitable for use in ELISA and Western Blot.
Detects a band at ~17kD in human brain (amygdala) and fetal mouse brain lysatesOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, pH 7.3, 0.02% sodium azide, 0.5% BSA.
Specificity：Recognizes human Alpha-synuclein. Expected to recognize both reported isoforms (NP_009292.1; NP_000336.1). Reported variants represent identical protein: NP_000336.1, NP_001139527.1, NP_001139526.1. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to C-ATGFVKKDQLGK, from the internal region of human Alpha-synuclein. Species sequence homology: rat, canine, porcine
