This proapoptotic activity is mediated predominantly through the activation of caspase-9.
It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases.
Applications:Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000Immunoprecipitation: 1:200Immunohistochemistry (Paraffin): 1:500Immunocytochemistry: 1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 10% glycerol. No preservative added.
Specificity:Recognizes human ASC. Species Crossreactivity: mouse
Clone # USB:AL177
Isotype:IgG
Calc Applications Abbrev:IC IHC IP WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to amino acids at the N-Terminal of human ASC