The dorsal ectoderm of the limb bud is known to regulate anterior-posterior patterning as well as dorsal-ventral patterning during vertebrate limb morphogenesis.
Wnt-7a, expressed in the dorsal ectoderm, encodes a key molecule implicated in these events.
In addition, Wnt-7a guides the development of the anterior-posterior axis in the female reproductive tract, and plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function.
Wnt-7a is required for the sexually dimorphic development of the mammalian reproductive tract.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human WNT7A. Species Crossreactivity: chimpanzee, gorilla, orangutan, gibbon, monkey, mouse, rat, bat, bovine, canine, guinea pig, hamster, equine, porcine, rabbit, chicken, xenopus
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Bo Ca Ch Eq Gp Hm Hu Mk Mo Po Rb Rt Xe
Immunogen：Synthetic peptide corresponding to 12aa from the internal region of human WNT7A.
