Somatostatin negatively regulates the growth of various normal and tumor cells via five somatostatin receptors.
Somatostatin receptors are expressed by a large variety of human tumors, and the predominant expression of SST2 receptors in tumor tissues forms the basis for the successful application of SST2-preferring agonists in the treatment of patients with GH-secreting pituitary adenomas, as well as in patients with carcinoid or islet cell tumors.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 15-20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human SSTR2. Species crossreactivity: monkey, mouse, rat, bovine, canine, gibbon, equine, hamster, porcine, rabbit
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Bo Ca Eq Hm Hu Mk Mo Po Rb Rt
Immunogen:Synthetic peptide corresponding to 17aa from 2nd extracellular domain of human SSTR2. Species sequence homology: bat.