ROR Gamma (RORC), an NR1 Thyroid Hormone-Like receptor, has been shown to affect thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis.
ROR gamma has been shown to promote thymocyte survival by activating the expression of the antiapoptotic protein Bcl-x(L).
ROR gamma is also required for the development of lymph nodes and Peyer's patches.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 15-20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human ROR Gamma. Species crossreactivity: gibbon, chimpanzee, gorilla, monkey and orangutan.
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Hu Mk
Immunogen:Synthetic peptide corresponding to 16aa from human ROR Gamma. Species sequence homology: bat, bovine, canine, equine and rabbit.