PTP alpha, a R4 receptor protein tyrosine phosphatase, is implicated in neuron formation, retinal development, cell adhesion, potassium channel regulation, nerve repair, insulin signaling, and cell cycle regulation.
PTP alpha activates the Src protein tyrosine kinase during mitosis, resulting in the transition from G2 to mitosis in the cell cycle.
PTP alpha is associated with carcinomas of breast, colon, oral squamous cell and prostate.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 4ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human PTPRA. Species crossreactivity: bat, gibbon, bovine, chicken, canine, xenopus, gorilla, hamster, equine, monkey, mouse, porcine, rabbit, rat and zebrafish.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Bo Ca Ch Eq Hm Hu Mk Mo Po Rb Rt Xe Ze
Immunogen：Synthetic peptide corresponding to 18aa from cytoplasmic domain of human PTPRA.
