P2Y12 is a Purinergic Receptor essential for the aggregation of blood platelets.
There is evidence that mutations in P2Y12 cause a bleeding disorder, suggesting that knowledge of the P2Y12 receptor could advance the development of antiplatelet agents to treat cardiovascular diseases.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human P2RY12/P2Y12. Species Crossreactivity: canine, equine, gorilla, gibbon, rabbit, monkey
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Ca Eq Hu Mk Rb
Immunogen：Synthetic peptide corresponding to 16aa from 1st cytoplasmic domain of human P2RY12/P2Y12. Species sequence homology: bat and porcine.
