P2Y11, the only Purinergic Receptor that acts via cAMP, may be involved in the differentiation of immunocytes.
Immature and mature dendritic cells express P2Y and P2X subtypes, including P2Y11, which are coupled to increases in intracellular Ca2+, membrane depolarization, and secretion of inflammatory cytokines.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 8ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human P2RY11/P2Y11. Species crossreactivity: gorilla, gibbon and equine.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Eq Hu
Immunogen：Synthetic peptide corresponding to 17aa from 3rd cytoplasmic domain of human P2RY11/P2Y11.
