P2Y1 is a Purinergic Receptor that causes a change in platelet shape and potentially leads to platelet aggregation by binding ADP, which results in the mobilization of intracellular calcium ions via activation of phospholipase C.
This receptor also mediates the release of the relaxing factor nitric oxide and may be involved in the modulation of neuronal signal transmission.
Applications:Suitable for use in Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 2-3ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human P2RY1. Species crossreactivity: bat, monkey, rabbit, gorilla, mouse, rat, bovine, canine, gibbon, guinea pig, hamster
Isotype：IgG
Calc Applications Abbrev：IC IHC
Calc Crossreactivity：Bo Ca Gp Hm Hu Mk Mo Rb Rt
Immunogen：Synthetic peptide corresponding to 15aa from the C-terminus of human P2RY1. Species sequence homology: equine and xenopus.
