Nuclear receptor TLX, a NR2 hepatocyte NF4-like receptor, has been shown to affect anterior brain differentiation, retinal development, and vision.
It has been suggested that TLX targets genes for RAR beta2 and Pax2 during retinal development.
Homozygous TLX mutant mice are viable at birth but exhibit reduced forebrain development and are more aggressive than wild-type mice.
Mice with deleted TLX locus exhibit cerebral hypoplasia, blindness, and extreme aggression
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 5.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human NR2E1. Species Crossreactivity: bat, gibbon, bovine, canine, gorilla, equine, monkey, porcine and rabbit.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Bo Ca Eq Hu Mk Po Rb
Immunogen：Synthetic peptide corresponding to 15aa from the N-terminus of human NR2E1. Species sequence homology: chicken, xenopus, hamster, mouse, rat and zebrafish.
