Metalloproteinase 13/Collagenase 3 (MMP13) was originally identified in breast carcinoma and has since been documented in a variety of tumors including chondrosarcomas, basal cell carcinoma, and malignant melanoma.
In addition it has been detected in inflammatory diseases such as atherosclerosis, in wound healing, and in destructive joint diseases such OA and RA.
MMP13 degrades the native helix of several types of fibrillar collagen, and extracellular matrix proteins in vitro.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 25ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human MMP13. Species Crossreactivity: gorilla, gibbon, monkey, equine, porcine, rabbit
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Eq Hu Mk Po Rb
Immunogen：Synthetic peptide corresponding to 18aa from the internal region of human MMP13. Species sequence homology: canine, hamster, mouse, rat and sheep.
