5-HT6, a Serotonin Receptor, appears to regulate cholinergic neurotransmission in the brain rather than the expected interaction as a modulator of dopaminergic transmission.
This interaction predicts a possible role for 5-HT6 Receptor antagonists in the treatment of learning and memory disorders.
The 5-HT6 Receptor is abundant in limbic areas, which participate in the control of mood and emotion.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human HTR6/5-HT36. Species crossreactivity: monkey, gorilla, rat, canine, gibbon, chimpanzee, hamster and equine.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Ca Eq Hm Hu Mk Rt
Immunogen：Synthetic peptide corresponding to 17aa from the C-terminus of human HTR6/5-HT36. Species sequence homology: mouse, bat, bovine and rabbit.
