H3 Histamine Receptor regulates the release of the neurotransmitters norepinephrine and somatostatin.
In histamine-containing neurons of the brain, the H3 receptor acts as a presynaptic autoreceptor, while in nonhistamine-containing neurons in both the central and peripheral nervous systems, it acts as a presynaptic heteroreceptor.
Multiple isoforms of H3 receptors are produced by alternative splicing.
Applications:Suitable for use in Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 18-36ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human HR3/Histamine H3 Receptor. Species crossreactivity: gibbon, gorilla and monkey.
Isotype：IgG
Calc Applications Abbrev：IC IHC
Calc Crossreactivity：Hu Mk
Immunogen：Synthetic peptide corresponding to 16aa from 3rd cytoplasmic domain of human HRH3/Histamine H3 Receptor.
