FZD6 is a Frizzled Receptor for Wnt signaling proteins involved in patterning during development.
Contrary to other Frizzled proteins, FZD6 does not contain a C-terminal PDZ domain-binding motif.
FZD6 is widely expressed.
The Drosophila homolog activates Dishevelled.
Applications:Suitable for use in Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 6-14ug/mlImmunocytochemistry: 3-6ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human Frizzled-6. Species crossreactivity: gibbon, gorilla, monkey and orangutan.
Isotype：IgG
Calc Applications Abbrev：IC IHC
Calc Crossreactivity：Hu Mk
Immunogen：Synthetic peptide corresponding to 16aa from the N-terminus of human Frizzled-6. Species sequence homology: mouse, bovine, canine, equine, porcine and rabbit.
