Frizzled-3 (FZD3) is a Frizzled Receptor that mediates Wnt signaling.
It is widely expressed, mostly in brain and urogenital tissues.
FZD3 is also expressed in the epidermis and developing hair follicles.
FZD3 has been implicated in the development of axon tracts in the forebrain.
A truncated form of FZD3 exists due to alternative splicing.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human FZD3/Frizzled 3. Species Crossreactivity: bovine, canine, hamster, equine, monkey, mouse, porcine, rabbit, rat, gorilla, gibbon and bat.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Bo Ca Eq Hm Hu Mk Mo Po Rb Rt
Immunogen：Synthetic peptide corresponding to 17aa from the N-terminus of human FZD3/Frizzled 3. Species sequence homology: chicken and xenopus.
