FZD7, a Frizzled Receptor, is a receptor for Wnt signaling proteins.
FZD7 downregulates the functions of the tumor suppressor gene APC and thereby enhances beta catenin-mediated signals.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 4ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human FZD7/Frizzled 7. Species crossreactivity: bat, monkey, gorilla, mouse, rat, bovine, canine, gibbon, hamster, porcine, rabbit
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Bo Ca Hm Hu Mk Mo Po Rb Rt
Immunogen:Synthetic peptide corresponding to 20aa from the N-terminus of human FZD7/Frizzled 7. Species sequence homology: xenopus.