Proteinase-Activated Receptor 4 (PAR4) is a member of the Proteinase-Activated Receptor subfamily.
Along with other protease-activated receptors, PAR4 mediates the effects of the enzyme, thrombin which include activation of platelets, leukocytes, endothelial cells, and mesenchymal cells at sites of vascular injury.
These cellular responses are triggered through proteolytic activation of the receptors by thrombin.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 2-5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human F2RL3/PAR4. Species crossreactivity: monkey.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu Mk
Immunogen：Synthetic peptide corresponding to 16aa from 2nd extracellular domain of human F2RL3/PAR4. Species sequence homology: gorilla and gibbon.
