The Proteinase-activated receptor 2 (PAR2) is a member of the proteinase-activated receptor subfamily.
It is activated through proteolytic exposure of an occult tethered ligand by trypsin and trypsin-like proteases.
This is in contrast to other members of the subfamily which are activated by the protease thrombin.
PAR2 has been implicated in acute inflammatory response, asthma, and pain transmission.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human F2RL1. Species Crossreactivity: gibbon.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to 18aa from 2nd extracellular domain of human rabbit. Species sequence homology: hamster, monkey, mouse and rat.
