EDG2, a Lysophospholipid/Lysosphingolipid Receptor, mediates growth factor-like activities such as proliferation, platelet aggregation, and chemotaxis.
EDG2 is involved in myelin formation or maintenance.
It is activated by platelet-derived lysophosphatidic acid (LPA), a lipid metabolite present in serum that acts ubiquitously.
Although alternate translation start codons and polyadenylation sites have been reported, the alternative splicing transcripts each encode identical proteins.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 2-3ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human EDG2. Species crossreactivity: bat, gibbon, bovine, chicken, canine, xenopus, gorilla, hamster, equine, monkey, mouse, porcine, rabbit, rat and sheep.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Bo Ca Ch Eq Hm Hu Mk Mo Po Rb Rt Sh Xe
Immunogen：Synthetic peptide corresponding to 19aa from 3rd cytoplasmic domain of human EDG2. Species sequence homology: zebrafish.
