DRD1, a Dopamine Receptor, mediates the effect of the neurotransmitter dopamine, an intermediate in the biosynthesis of noradrenaline and adrenaline.
It is involved in the control of motor activity and cognitive memory.
Downregulation of DRD1 leads to severe impairments in working memory and to locomotor hyperactivity, which are observed in diseases such as schizophrenia, Parkinson's disease, affective disorders, and attention deficit hyperactivity disorder.
Applications:Suitable for use in Immunohistochemistry.
Not suitable for Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 8ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human DRD1. Species crossreactivity: gorilla, gibbon, monkey, bovine, canine and porcine.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Bo Ca Hu Mk Po
Immunogen：Synthetic peptide corresponding to 15aa from 3rd cytoplasmic domain of human DRD1. Species sequence homology: mouse, bat and hamster.
