DPP10 shares structural similarity with the dipeptidyl peptidase family, however it lacks the active site serine, which is substituted with a glycine residue.
DPP10 has been shown to facilitate Kv4.2 protein trafficking to the cell membrane, increase A-type current magnitude and modify the voltage dependence and kinetic properties of the Kv4.2 channel.
DPP10 is prominently expressed in all brain regions examined except cerebellum.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human DPP10. Species Crossreactivity: gorilla, gibbon, monkey, marmoset, elephant, panda, bovine, canine, bat, equine, rabbit, porcine
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Bo Ca Eq Hu Mk Po Rb
Immunogen：Synthetic peptide corresponding to 14aa from the extracellular domain of human DPP10. Species sequence homology: mouse, rat and hamster.
