The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors.
DRD2 may be linked to alcoholism and other substance-use disorders.
Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson's disease.
Three alternatively spliced isoforms have been identified.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human Dopamine D2 Receptor. Species Crossreactivity: bat, bovine, chimpanzee, canine, gorilla, equine and rabbit.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Bo Ca Eq Hu Rb
Immunogen：Synthetic peptide corresponding to 16aa from 3rd cytoplasmic domain of human Dopamine D2 Receptor. Species sequence homology: gibbon, monkey and porcine.
