RDC1 was originally considered to be an Adrenomedullin receptor that binds calcitonin gene-related peptide (CGRP) and adrenomedullin.
RDC1 and GPRN1 represent two tissue-specific subtypes of the same 60kD receptor.
RDC1 has the structural characteristics of a chemokine receptor.
Recently it has been shown that RDC1 binds to the chemokine CXCL12 and should be considered to be a chemokine receptor.
Applications:Suitable for use in Immunohistochemistry and Western Blot.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 4ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human CXCR7. Species crossreactivity: equine.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Eq Hu
Immunogen：Synthetic peptide corresponding to 17aa from 3rd cytoplasmic domain of human CXCR7. Species sequence homology: gorilla, gibbon, monkey and canine.
